Apples may help ward off colon cancer

Apples may help ward off colon cancer - NutraIngredients.com
2008.03.28
" Apple pectin and polyphenol-rich apple juice have an anticarcinogenic effect on the colon, encouraging the production of suspected chemopreventative metabolite butyrate, say researchers. Butyrate is a short chain fatty acid (SCFA) that has been found to be a major factor contributing to healthy colon mucosa..."Butyrate not only serves as a major nutrient for the colon epithelia but is also thought to play an important role in the protective effect of natural fibre against colorectal cancer,"...A recent study in California found low doses of freeze-dried grape powder could inhibit the development of colorectal cancer thanks to the polyphenol resveratrol and synergistic effects between the grape compounds...When the butyrate content was high, HDAC was inhibited. With slower production of HDAC, there would be significantly less growth of precancerous and tumour cells..."

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Low-carb diet bad for gut health?

Low-carb diet bad for gut health? NutraIngredients.com 6/19/07 "Eating a low-carbohydrate diet, like the once fashionable Atkins diet, may adversely affect the numbers of certain types of bacteria in the gut of obese men...may also adversely affect the gut bacterial populations that beneficially produce a substance called butyrate, which has been shown to be important for keeping the gut healthy including helping to prevent colorectal cancer..."The changes in faecal butyrate in the present study represent the largest reported in a human dietary trial and provide the strongest evidence to date that butyrate production is largely determined by the content of fermentable carbohydrate in the diet," wrote lead author Sylvia Duncan..."Furthermore, this study has provided clear evidence that the proportions of certain groups of colonic bacteria, as monitored in faecal samples, respond to dietary carbohydrate intake," ...Levels of so-called beneficial bacteria, particularly the bifidobacteria were also detrimentally affected by decreasing carb levels..."

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