Red wine antioxidant, resveratrol, may kill cancer cells

Red wine antioxidant may kill cancer cells: NutraIngredients.com
2008.03.27
"The antioxidant resveratrol, found in grape skins and red wine, can cripple the function of pancreatic cancer cells while sensitising them to chemotherapy...As well as disabling the function of the cancer cells by reaching and reacting with the mitochondria (the cell's energy source), researchers found that when they were pre-treated with resveratrol before being irradiated, it resulted in a type of cell death called apoptosis...The study found that resveratrol reduced the function of proteins in the pancreatic cancer cell membranes responsible for pumping chemotherapy out of the cell, therefore making them more sensitive to the treatment...Additionally, the antioxidant triggered the production of reactive oxygen species (ROS), causing apoptosis, and depolarised the mitochondrial membranes, indicating a decrease in the cell's potential to function...The researchers said the discovery is important because the mitochnodria contains its own DNA and can continuously supply the cell with energy when functioning fully. Stopping the energy flow can therefore help stop cancer..."

Mounting Evidence Shows Red Wine Antioxidant Kills Cancer - Science Daily on same story
2008.03.27
"...Yet despite widespread interest in antioxidants, some physicians are concerned antioxidants might end up protecting tumors. Okunieff's study showed there is little evidence to support that fear. In fact, the research suggests resveratrol not only reaches its intended target, injuring the nexus of malignant cells, but at the same time protects normal tissue from the harmful effects of radiation..."

Grape Skin Compound (resveratrol) Fights The Complications Of Diabetes: "ScienceDaily (Mar. 20, 2008) — Research carried out by scientists at the Peninsula Medical School in the South West of England has found that resveratrol, a compound present naturally in grape skin, can protect against the cellular damage to blood vessels caused by high production of glucose in diabetes, according to a recently published paper in the science journal 'Diabetes, Obesity and Metabolism.'"

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