Dietary trans fatty acids may be linked to fetal loss

Dietary trans fatty acids may be linked to fetal loss - Yahoo! News:
Thu Sep 18, 2008
"NEW YORK (Reuters Health) - Trans fatty acids, the much maligned 'solid' fats implicated as artery-clogging contributors to cardiovascular disease, may also increase the risk of fetal death during pregnancy, study findings suggest...Earlier studies have also found a relationship between a diet high in trans fatty acids and increased insulin resistance. This, in turn, increases the activity of plasminogen activator inhibitor, which has been associated with fetal loss...After categorizing the study population according to average trans fat intake, the investigators found the rate of fetal loss increased from 30 percent among those with the lowest intake of trans fat in the diet (2.2 percent of total calories on average) to 52 percent among women with the highest intake of trans fat (defined as 4.7 percent of total calories)...As the percent of calories from trans fat increased, so did the risk of having one or more fetal losses, Glueck and colleagues report. This association was independent of body mass, insulin and glucose levels, and other factors potentially associated with risk for fetal loss..."

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