Studies show how fruits and veggies reduce cancer

Studies show how fruits and veggies reduce cancer - Yahoo! News
2007.12.07
"Just three servings a month of raw broccoli or cabbage can reduce the risk of bladder cancer by as much as 40 percent...These foods are rich in compounds called isothiocyanates, which are known to lower cancer risk..."Cooking can reduce 60 to 90 percent of ITCs, (isothiocyanates)," Dr. Li Tang...A second team of researchers from Roswell Park tested broccoli sprouts in rats.They used rats engineered to develop bladder cancer and fed some of them a freeze-dried extract of broccoli sprouts. The more they ate, the less likely they were to develop bladder cancer, said Dr. Yuesheng Zhang"...In a third study, a team at The Ohio State University fed black raspberries to patients with Barrett's esophagus, a condition that can lead to esophageal cancer...Ohio State's Laura Kresty and colleagues fed 1.1 ounces (32 grams) of freeze-dried black raspberries to women with Barrett's esophagus and 1.6 ounces (45 grams) to men every day for six months...They measured urine levels of levels of two compounds -- 8-isoprostane and GSTpi -- that indicate whether cancer-causing processes are going on in the body...Kresty said 58 percent of patients had marked declines of 8-isoprostane levels, suggesting less damage, and 37 percent had higher levels of GSTpi, which can help interfere with cancer causing damage and which is usually low in patients with Barrett's."


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Flavonols seem to lower chance of getting pancreatic cancer

Flavonols may help ward off pancreatic cancer Reuters/Yahoo!News " look at the eating patterns of 183,518 California and Hawaii residents has found evidence that a diet high in flavonols might help ward off pancreatic cancer...Flavonols are found in plant-based foods with onions, apples, berries, kale, and broccoli having the highest concentrations...People who had the largest amount of flavonols in their diet -- measured with a "food frequency" questionnaire -- had a 23-percent lower risk of developing pancreatic cancer compared with people with the lowest levels, Dr. Ute Nthlings from the German Institute of Human Nutrition Potsdam-Rehbruecke reported...Smokers benefited most, presumably because they are at high risk for pancreatic cancer already. Smokers who ate the most flavonols reduced their risk of developing pancreatic cancer by 59 percent...Of the three individual flavonols studied (kaempferol, quercetin and myricetin), kaempferol, abundant in spinach and some cabbages, was associated with the largest risk reduction (22 percent) among all study subjects... the anti-cancer effects of these compounds, in general, have been attributed to their ability to inhibit cell growth and oxidative stress, and induce detoxification enzymes and programmed cell death..."

A major rethink of the way certain antioxidants work needs to happen. To cause apoptosis, or to limit blood flow to cancers is not merely a function of limiting free radical damage in the body. Certain "antioxidants" are obviously much, much more than antioxidants. They redirect the functioning of specific parts of the body, often in a beneficial way. Just take a look at the myriad functions of EGCG, or curcumin in the human body and it becomes apparent that their antioxidant ability appears to be only a small part of their function. It seems we need another word for such compounds. But what? At least we can agree to rule out adaptogen right? Something more grounded in science and with a specific definition that refers to specific functioning of such compounds. We can dress it in old, latiny roots. The anti-rolemodel is... "An adaptogen produces a nonspecific response in the body..." lovely.

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Cruciferous vegetables and cancer

Nutrients In Certain Vegetables May Provide Cancer-fighting Benefit ScienceDaily 3/17/07 "Chemicals in cruciferous vegetables, such as broccoli, watercress, cabbage and cauliflower, appear to not only stop human prostate cancer cells from growing in mice but also may cut off the formation of blood vessels that "feed" tumors, says a University of Pittsburgh Cancer Institute study...Dr. Singh's study is based on phytochemicals, called isothiocyanates (ITCs), found in several cruciferous vegetables and generated when vegetables are either cut or chewed. His laboratory has found that phenethyl-ITC, or PEITC, is highly effective in suppressing the growth of human prostate cancer cells at concentrations achievable through dietary intake..."Angiogenesis is a major issue in cancer metastases," said Dr. Singh. "Our results provide promising preliminary evidence that constituents of many edible cruciferous vegetables may slow down, or even halt, this process.""

Quite amazing that at dietary levels these vegetables can have a strong antiangiogenesis effect.

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