Monday, March 31, 2008

Red wine antioxidant, resveratrol, may kill cancer cells

Red wine antioxidant may kill cancer cells: NutraIngredients.com
2008.03.27
"The antioxidant resveratrol, found in grape skins and red wine, can cripple the function of pancreatic cancer cells while sensitising them to chemotherapy...As well as disabling the function of the cancer cells by reaching and reacting with the mitochondria (the cell's energy source), researchers found that when they were pre-treated with resveratrol before being irradiated, it resulted in a type of cell death called apoptosis...The study found that resveratrol reduced the function of proteins in the pancreatic cancer cell membranes responsible for pumping chemotherapy out of the cell, therefore making them more sensitive to the treatment...Additionally, the antioxidant triggered the production of reactive oxygen species (ROS), causing apoptosis, and depolarised the mitochondrial membranes, indicating a decrease in the cell's potential to function...The researchers said the discovery is important because the mitochnodria contains its own DNA and can continuously supply the cell with energy when functioning fully. Stopping the energy flow can therefore help stop cancer..."

Mounting Evidence Shows Red Wine Antioxidant Kills Cancer - Science Daily on same story
2008.03.27
"...Yet despite widespread interest in antioxidants, some physicians are concerned antioxidants might end up protecting tumors. Okunieff's study showed there is little evidence to support that fear. In fact, the research suggests resveratrol not only reaches its intended target, injuring the nexus of malignant cells, but at the same time protects normal tissue from the harmful effects of radiation..."

Grape Skin Compound (resveratrol) Fights The Complications Of Diabetes: "ScienceDaily (Mar. 20, 2008)Research carried out by scientists at the Peninsula Medical School in the South West of England has found that resveratrol, a compound present naturally in grape skin, can protect against the cellular damage to blood vessels caused by high production of glucose in diabetes, according to a recently published paper in the science journal 'Diabetes, Obesity and Metabolism.'"

Food Compounds That Kill Test-Tube Cancer Cells Analyzed



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Apples may help ward off colon cancer

Apples may help ward off colon cancer - NutraIngredients.com
2008.03.28
" Apple pectin and polyphenol-rich apple juice have an anticarcinogenic effect on the colon, encouraging the production of suspected chemopreventative metabolite butyrate, say researchers. Butyrate is a short chain fatty acid (SCFA) that has been found to be a major factor contributing to healthy colon mucosa..."Butyrate not only serves as a major nutrient for the colon epithelia but is also thought to play an important role in the protective effect of natural fibre against colorectal cancer,"...A recent study in California found low doses of freeze-dried grape powder could inhibit the development of colorectal cancer thanks to the polyphenol resveratrol and synergistic effects between the grape compounds...When the butyrate content was high, HDAC was inhibited. With slower production of HDAC, there would be significantly less growth of precancerous and tumour cells..."

Regular, Long-term Aspirin Use Reduces Risk Of Colorectal Cancer, Study Suggests

Colon Cancer A Disease Of Hormone Deficiency, Scientists Suggest

'Western' Diet Linked To Increased Risk Of Colon Cancer Recurrence

Grape Powder Blocks Genes Linked To Colon Cancer

Grape Seed Extract Halts Cell Cycle, Checking Growth Of Colorectal Tumors In Mice

Dietary Ginger May Work Against Cancer Growth

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Vitamin A may suppresses type 1 diabetes

Vitamin A may suppresses type 1 diabetes - NutraIngredients.com
2008.03.31
" High levels of vitamin A may curb the onset of type 1 diabetes by protecting against the attack of insulin-producing beta cells...in mice and found that vitamin A consumption resulted in lower levels of tumour necrosis factor-alpha (TNF-alpha), a protein that has been linked in other studies to type 1 diabetes...Because vitamin A deficiency can directly impair cytotoxic T cell responses, it is plausible that both vitamin A deficiency and excess can affect the development of diabetes via different effects on the beta cell-specific immune response,"...After seven months, only 25 per cent of the mice consuming large quantities of vitamin A and 33 per cent of those eating diets enriched with grape-powder had developed type 1 diabetes...In contrast, 71 per cent of those on the non-enriched control diet had become diabetic..."

Previously Unrecognized Testosterone Deficiency Common In Men With Type 1 Diabetes

Once-irrelevant Compound May Have Medical Role In Preventing Diabetes Complications

Phase I Diabetes Trial Aims To Reverse Type 1 Diabetes


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Saturday, March 29, 2008

Prenatal omega-3 may aid babies' brain development

Prenatal omega-3 may aid babies' brain development - Yahoo! News
2008.02.27
"...among 109 Inuit infants they followed, those whose umbilical-cord blood was higher in docosahexaenoic acid, an omega-3 acid, at birth did better in tests of infant brain and eye development at the ages of 6 and 11 months...The new findings, reported in the Journal of Pediatrics, highlight the particular importance of DHA in the mothers' diet during the third trimester, when fetal brain development accelerates...There was no correlation, however, between the infants' test performance and DHA from breast milk. It's likely, according to Jacobson's team, that mothers' third-trimester DHA intake is more important than babies' consumption of breast-feeding because of the "critical third trimester brain growth spurt."...Besides fish, such as tuna and salmon, other DHA sources include fish oil supplements and algae-derived DHA..."

A bit more evidence of the power of DHA supplements during the prenatal period, especially the second half of pregnancy. Prenatal choline is probably the most important brain booster during the prenatal period. Moderate exercise during pregnancy is also another brain booster.

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Friday, March 14, 2008

Vitamin D pills may protect kids from type-1 diabetes

Vitamin D pills may protect kids from type-1 diabetes - NutraIngredients.com
2008.03.13
"...According to data from five observational studies, infants who received vitamin Dtype-1 diabetes than non-supplemented infants, reports the review in the Archives of Disease in Childhood...No randomised controlled trials were found in the literature, and the conclusions were drawn only from the five observational studies...In addition to an approximate 30 per cent reduction in the risk of developing type-1 diabetes, Zipitis and Akobeng also noted "some evidence of a dose-response effect, with those using higher amounts of vitamin D being at lower risk of developing type 1 diabetes."...They also noted that timing of the supplementation could also be a factor in the type-1 diabetes risk, with supplementation of vitamin D-rich cod liver oil between the ages of seven and 12 months at a 45 per cent lower risk, compared to infants supplemented between 0 and six months of age...The mechanism by which vitamin D supplementation may protect against the development of the disease is unclear, said the researchers, but evidence does exist that vitamin D may play a role in the immune system. There are also suggestions that vitamin D vitamin may prevent dysfunction in beta-cells (cells in the pancreas) caused by a class of proteins called cytokines...n September 2007, researchers from the University of Colorado at Denver reported that an increased intake of omega-3 fatty acids from marine sources may reduce a child's risk of developing type-1 diabetes by 55 per cent..." supplements were 29 per cent less likely to develop


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Aspirin use may prevent asthma

Aspirin use may prevent asthma, study finds - Yahoo! News:
2008.03.12
"...women who took a small dose of aspirin -- 100 mg every other day -- were 10 percent less likely to develop asthma over 10 years than women given placebos...Kurth's team studied 37,000 female healthcare professionals taking part in a study called the Women's Health Study. All were aged 45 and above, and had no serious illness, allergy or asthma at the start of the study...Women who were obese, with a body mass index of 30 or above, got no benefit from aspirin..."The effect of aspirin on adult-onset asthma was not significantly modified by age, smoking status, exercise levels, postmenopausal hormone use or randomized vitamin E assignment,"...

Aspirin can affect compounds involved in inflammation and the hyper-response of airways that is seen in asthma.

The researchers noted that between 4 percent and 11 percent of patients with asthma have an acute response to aspirin."


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Thursday, March 13, 2008

Breast-feeding seen to curb type 2 diabetes later

Breast-feeding seen to curb type 2 diabetes later - Yahoo! News:
2008.03.13
"'Dramatic increases in childhood obesity and the emergence
of type 2 diabetes in youth motivate research to identify
lifestyle approaches to primary prevention of both conditions,'
write Dr. Elizabeth J. Mayer-Davis of the
University of South
Carolina, Columbia
, and colleagues...The breast-feeding rate was lower in subjects with type 2 diabetes compared with the control subjects, at 20 versus 27 percent in African Americans; 50 versus 84 percent for Hispanics; and 39 percent versus 78 percent for non-Hispanic whites, respectively....Regardless of ethnic group, further analysis indicated that the protective effect of breast feeding against type 2 diabetes was in large part attributable to its effect in moderating current childhood weight.Nonetheless, breast-feeding in itself had a protective effect..."

Related articles...

Breastfeeding may help explain weight disparities - Yahoo! News:

Breast-feeding enhances kids' eyesight Reuters/Yahoo!News

Kentucky Study Shows Breast-Feeding Increases Babies' IQ:


Vitamin D may curb type 2 diabetes risk - Yahoo! News

ScienceDaily: Red Wine Ingredient -- Resveratrol -- Fights Diabetes In Mice


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Tuesday, March 11, 2008

Diesel fumes can affect your brain

Diesel fumes can affect your brain, scientists say - Yahoo! News:
2008.03.10
"Previous studies have found very small particles of soot,
or nanoparticles, are able to travel from the nose and lodge in
the brain. But this is the first time researchers have
demonstrated a change in brain activity..."It is conceivable that the long-term effects of exposure to traffic nanoparticles may interfere with normal brain function and information processing."...After about 30 minutes, brain wave patterns displayed a stress response, suggesting changes in information processing in the brain cortex...the result appears to be another black mark for nanoparticles found in traffic fumes, which have already been linked with increased rates of respiratory and cardiovascular disease..."


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Monday, March 10, 2008

Magnesium-rich foods ward off stroke in smokers

Magnesium-rich foods ward off stroke in smokers - Yahoo! News:
2008.03.10
"Their study of 26,000 male smokers in Finland found that
those whose diets were high in magnesium had a significantly
lower risk of one type of stroke... it may be that magnesium helps reduce high blood pressure, which can lead to stroke if untreated...The effect was stronger for men younger than 60 and the study also found that calcium, potassium and sodium intake were not associated with risk for any type of stroke...foods high in magnesium are black beans, broccoli, halibut, peanuts, oysters, rockfish and spinach..."


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Friday, March 7, 2008

Broccoli May Help Boost Aging Immune System

Broccoli May Help Boost Aging Immune System: ScienceDaily
2008.03.06
"... sulforaphane, a chemical in broccoli, switches on a set of antioxidant genes and enzymes in specific immune cells, which then combat the injurious effects of molecules known as free radicals that can damage cells and lead to disease..."As we age, the ability of the immune system to fight disease and infections and protect against cancer wears down as a result of the impact of oxygen radicals on the immune system," Nel said...According to the UCLA study, the ability of aged tissues to reinvigorate their antioxidant defense can play an important role in reversing much of the negative impact of free radicals on the immune system..."Our defense against oxidative stress damage may determine at what rate we age, how it will manifest and how to interfere in those processes," Nel said. "In particular, our study shows that a chemical present in broccoli is capable of stimulating a wide range of antioxidant defense pathways and may be able to interfere with the age-related decline in immune function."...The UCLA team not only found that the direct administration of sulforaphane in broccoli reversed the decline in cellular immune function in old mice, but they witnessed similar results when they took individual immune cells from old mice, treated those cells with the chemical outside the body and then placed the treated cells back into a recipient animal...In particular, the scientists discovered that dendritic cells, which introduce infectious agents and foreign substances to the immune system, were particularly effective in restoring immune function in aged animals when treated with sulforaphane..."We found that treating older mice with sulforaphane increased the immune response to the level of younger mice," said Hyon-Jeen Kim, first author and research scientist at the Geffen School...sulforaphane interacts with a protein called Nrf2, which serves as a master regulator of the body's overall antioxidant response and is capable of switching on hundreds of antioxidant and rejuvenating genes and enzymes... "

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Thursday, March 6, 2008

Happiness can be inherited

Happiness can be inherited, research finds - Yahoo! News
2008.03.08
"...A study of nearly 1,000 pairs of identical and non-identical twins found genes control half the personality traits that make people happy while factors such as relationships, health and careers are responsible for the rest of our well-being...People who are sociable, active, stable, hardworking and conscientious tend to be happier, the researchers reported in the journal Psychological Science..."

Genes Hold The Key To How Happy We Are, Scientists Say - ScienceDaily

Interesting research, if true, but a great example of absurdly low fact content in the articles... lets hope for more details.

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Wednesday, March 5, 2008

Breastfeeding may help explain weight disparities

Breastfeeding may help explain weight disparities - Yahoo! News:
"Researchers found that among 739 10- to 19-year-olds, those
who had been breastfed for more than four months had a lower
average body mass index (BMI), and lower odds of being
overweight...Researchers also speculate that breast milk itself may have lasting metabolic effects that aid in weight control...Breastfed babies have a lower risk of illnesses like diarrhea and middle-ear infections, and breastfeeding has also been linked to lower odds of allergies, asthma and childhood leukemia..."


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Monday, March 3, 2008

Why winter is "flu season"

U.S. study shows why winter is "flu season" - Yahoo! News: (Reuters) -
2008.03.02
Influenza viruses coat themselves in fatty material that hardens and protects them in colder
temperatures -- a finding that could explain why winter is the flu season...This butter-like coating melts in the respiratory tract, allowing the virus to infect cells..."It's only in this liquid phase that the virus is capable of entering a cell to infect it." Experts have long pondered why flu and other respiratory viruses spread more in winter. No one explanation, such as people staying indoors more, or the destructive effect of the sun's radiation in summer, has fully explained it...In warmer outdoor temperatures this protective coating melts, and unless it is inside a living person or animal, the virus perishes..."


Makes one think that if a pandemic hits the northern hemisphere... head south.

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