B vitamins vital before conception - NutraIngredients.com
2007.12.06
"The importance of B vitamins, particularly folate, in foetal development is well established. The new study expands our understanding of the potential of pre-conception diets to influence the health of offspring...."The data provide the first evidence that clinically relevant reductions in specific dietary inputs to the methionine/folate cycles during the periconceptional period can lead to widespread epigenetic alterations to DNA methylation in offspring, and modify adult health-related phenotypes," wrote lead author Kevin Sinclair...The authors explain that DNA methylation is key to the maintenance of gene silencing. The process relies on a dietary supply of methyl groups, as provided by B vitamins."
The study was on sheep, but plenty of studies show a similar effect in a variety of mammals including humans.
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