Sedentary Lifestyles Associated With Accelerated Aging Process - ScienceDaily
2008.01.29
"Individuals who are physically active during their leisure time appear to be biologically younger than those with sedentary lifestyles...Regular exercisers have lower rates of cardiovascular disease, type 2 diabetes, cancer, high blood pressure, obesity and osteoporosis, according to background information in the article. "A sedentary lifestyle increases the propensity to aging-related disease and premature death," the authors write. "Inactivity may diminish life expectancy not only by predisposing to aging-related diseases but also because it may influence the aging process itself."...Telomere length decreased with age, with an average loss of 21 nucleotides (structural units) per year. Men and women who were less physically active in their leisure time had shorter leukocyte telomeres than those who were more active. "Such a relationship between leukocyte telomere length and physical activity level remained significant after adjustment for body mass index, smoking, socioeconomic status and physical activity at work," the authors write. "The mean difference in leukocyte telomere length between the most active [who performed an average of 199 minutes of physical activity per week] and least active [16 minutes of physical activity per week] subjects was 200 nucleotides, which means that the most active subjects had telomeres the same length as sedentary individuals up to 10 years younger, on average." A sub-analysis comparing pairs in which twins had different levels of physical activity showed similar results...Oxidative stress--damage caused to cells by exposure to oxygen--and inflammation are likely mechanisms by which sedentary lifestyles shorten telomeres, the authors suggest. In addition, perceived stress levels have been linked to telomere length. Physical activity may reduce psychological stress, thus mitigating its effect on telomeres and the aging process..."
Rounding 3rd and heading for home in this batch of research showing that exercise not only makes you healthier it'll probably make you live longer and vice versa for lethargy.
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Tuesday, January 29, 2008
Sedentary Lifestyles Associated With Accelerated Aging Process
Labels:
aging,
Exercise,
leukocyte telomeres,
nucleotides,
sedantary,
telomeres
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