Wednesday, June 25, 2008
Low Vitamin D Levels Associated With Death From Cardiovascular, All Causes
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Salutary Pizza Spice: Oregano Helps Against Inflammations
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Turmeric (curcumin) Shows Promise In Combating Diabetes And Obesity
2008.06.23
"...turmeric-treated mice were less susceptible to developing Type 2 diabetes, based on their blood glucose levels, and glucose and insulin tolerance tests. They also discovered that turmeric-fed obese mice showed significantly reduced inflammation in fat tissue and liver compared to controls. They speculate that curcumin, the anti-inflammatory, anti-oxidant ingredient in turmeric, lessens insulin resistance and prevents Type 2 diabetes in these mouse models by dampening the inflammatory response provoked by obesity....For now, the conclusion that Dr. Tortoriello and his colleagues have reached is that turmeric -- and its active anti-oxidant ingredient, curcumin -- reverses many of the inflammatory and metabolic problems associated with obesity and improves blood-sugar control in mouse models of Type 2 diabetes."
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Thursday, June 19, 2008
Cranberries, probiotics may fight ulcer-causing bacteria in children
2008.06.19
" Cranberry juice or probiotics clear the stomach of children of a bacterial strain known to cause ulcers and cancer...Helicobacter pylori...Gotteland and co-workers recruited the children, aged between six and 16, and randomly assigned them to one of four groups: placebo juice plus heat-killed La1 (control), cranberry juice plus La1 (CB/La1), placebo juice plusLa1 (La1), and cranberry juice plus heat-killed La1 (CB). The cranberry juice (200 ml, Cran Chile) and La1 (80ml, Chamyto, Nestlé Chile SA), or placebo versions were given daily for three weeks...A significant reduction in H. pylori was observed all three active groups, with the La1, CB, and CB/La1 groups showing eradication rates of 14.9, 16.9, and 22.9 per cent, compared to only 1.5 per cent in the control group..."
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Wednesday, June 18, 2008
Revolutionary Cancer Treatment
2008.06.18
"Researchers Mass-Produced Cells to Destroy an Incurable Skin Cancer...In this experiment, researchers took blood from a melanoma patient who was near death and from that blood extracted a type of cell that's actually programmed by the body to attack cancer, CD4 + T cells..."It's targeted to tumor cells and not to normal cells," Dr. Cassian Yee of the Fred Hutchison Cancer Research Center in Seattle, the lead author of the study, told ABC News. The researchers even isolated which of those cancer-fighting cells were most aggressive against the patient's own melanoma and then, over the next three months, grew a vast, new army of five billion of those particular cells. Finally, the scientists injected the cancer-fighting cells back into the patient...The results were stunning. Before the treatment, the cancer had spread through his lymph nodes. Just two months after treatment, CT and PET scans showed no sign of cancer anywhere in the patient's body. Two years later, the patient still showed no signs of cancer...researchers say the potential of this approach may be much broader. "The use of these cancer-fighting cells can be used to treat other types of cancer, like breast cancer or prostate cancer or lung cancer. Those studies have not been done yet," Yee said.But when it comes to advanced skin cancer, scientists are off to a promising start -- a new weapon against a disease that has been so vexing."
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Vitamin D helps colorectal cancer patients: study - Yahoo! News
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Monday, June 16, 2008
Vitamin D: New Way To Treat Heart Failure?
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Red Wine's Resveratrol May Help Battle Obesity
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Healthy lifestyle triggers genetic changes
2008.06.16
"The men underwent three months of major lifestyle changes, including eating a diet rich in fruits, vegetables, whole grains, legumes and soy products, moderate exercise such as walking for half an hour a day, and an hour of daily stress management methods such as meditation...As expected, they lost weight, lowered their blood pressure and saw other health improvements. But the researchers found more profound changes when they compared prostate biopsies taken before and after the lifestyle changes...After the three months, the men had changes in activity in about 500 genes -- including 48 that were turned on and 453 genes that were turned off... The activity of disease-preventing genes increased while a number of disease-promoting genes, including those involved in prostate cancer and breast cancer, shut down... The research was led by Dr. Dean Ornish, head of the Preventive Medicine Research Institute in Sausalito, California, and a well-known author advocating lifestyle changes to improve health..."often people say, 'Oh, it's all in my genes, what can I do?' Well, it turns out you may be able to do a lot"..." "'In just three months, I can change hundreds of my genes simply by changing what I eat and how I live?"..."
Showing yet again how pliable our genome is. If this story doesn't further the message that genes are not a fixed fate, I'm not sure what will.
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Age At Puberty Linked To Mother's Prenatal Diet
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Wednesday, June 11, 2008
Bright Light Improves Dementia Symptoms and Depression
2008.06.10
"Turning up the lights during the daytime may boost mood and improve behavior in elderly adults with dementia...Environmental light affects the body's 24-hour biological clock, also known as the circadian rhythm. Too little light exposure can throw off the sensitive balance of the circadian timing system. Disturbances in circadian rhythm can lead to sleep woes. A hormone called melatonin also plays an important role in the maintaining the system's circadian rhythm...
The researchers learned that bright light resulted in a modest improvement in dementia symptoms. Specifically, the use of bright daytime lighting:
- Reduced cognitive scores on a mental status exam by a relative 5%.
- Cut depression symptoms by a relative 19%.
- Calmed slow increases in functional limitations by slightly more than half (53%).
Adding melatonin helped patients fall asleep about eight minutes faster and sleep longer by 27 minutes. The researchers recommend melatonin supplements only in combination with light. Melatonin combined with brighter lighting cut agitated behavior by 9%..."
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2008.06.11
"...A popular vitamin supplement aimed at diabetics is not as effective as most advertisements for it claim...benfotiamine -- a synthetic derivative of the vitamin B1 -- does not actually dissolve and penetrate cell membranes as well as the researchers say is often claimed...lab tests showed that benfotiamine as sold to consumers was not lipid-soluble -- which means it did not dissolve in organic solvents and oils to boost health by working quickly..."
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Wednesday, June 4, 2008
Dehydrated Tomatoes Show Promise For Preventing Prostate Cancer
2008.06.02
"The protective effect of tomato products against prostate cancer has been suggested in many studies, but researchers remain uncertain about the exact mechanisms. Mossine and colleagues demonstrated that FruHis, an organic carbohydrate present in dehydrated tomato products, exerts a strong protective effect...Animals fed the tomato paste plus FruHis diet had the longest survival from cancer at 51 weeks compared with 50 weeks in the tomato powder group, 45 weeks in the tomato paste alone group and 40 weeks in the control group...Mossine said the protective effect of tomato-based products was restricted to prostate tumors, which is consistent with other research on tomatoes and cancer. Incidence of other tumors was too small to examine...In vitro, Mossine and colleagues evaluated the anti-cancer properties of FruHis and 14 other D-fructose amino acids and found that FruHis in a concentrated form protected against DNA damage known to lead to prostate cancer. When combined with lycopene, FruHis stopped cancerous cell growth more than 98 percent of the time..."FruHis may represent a novel type of potential dietary antioxidant. Experiments like these suggest that a combination of FruHis and lycopene should be investigated as a potential therapeutic anti-tumor agent, not just a prevention strategy."..."
Worried About Prostate Cancer? Tomato-broccoli Combo Shown To Be Effective: "ScienceDaily (Jan. 16, 2007) — A new University of Illinois study shows that tomatoes and broccoli--two vegetables known for their cancer-fighting qualities--are better at shrinking prostate tumors when both are part of the daily diet than when they're eaten alone."
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Scientists revive the debate on cellphones and cancer
2008.06.03
"What do brain surgeons know about cellphone safety that the rest of us don't?...Along with Senator Edward Kennedy's recent diagnosis of a glioma, a type of tumor that critics have long associated with cellphone use, the doctors' remarks have helped reignite a long-simmering debate about cellphones and cancer...the studies are observational, showing only an association between cellphone use and cancer, not a causal relationship. The most important of these studies is called Interphone, a vast research effort in 13 countries, including Canada, Israel and several in Europe...Some of the research suggests a link between cellphone use and three types of tumors: glioma; cancer of the parotid, a salivary gland near the ear; and acoustic neuroma, a tumor that essentially occurs where the ear meets the brain. All these cancers are rare...Last year, The American Journal of Epidemiology published data from Israel finding a 58 percent higher risk of parotid gland tumors among heavy cellphone users. Also last year, a Swedish analysis of 16 studies in the journal Occupational and Environmental Medicine showed a doubling of risk for acoustic neuroma and glioma after 10 years of heavy cellphone use...."
Radiation From Mobile Phones Changes Protein Expression In Living People, Study Suggests:
ScienceDaily (Feb. 25, 2008) — A new study completed by the Finnish Radiation and Nuclear Safety Authority (STUK) on effects of mobile phone radiation on human skin strengthens the results of the human cell line analyses: living tissue responds to mobile phone radiation..."
Heavy Cell Phone Use Linked To Cancer, Study Suggests: "ScienceDaily (Feb. 15, 2008) — An Israeli scientist, Dr. Siegal Sadetzki, has found a link between cell phone usage and the development of tumors."
Cell Phones Risky during Pregnancy?
"...Kids whose mothers used cell phones while pregnant had a 54% higher risk of behavior problems -- emotional problems, hyperactivity, conduct problems, and peer problems. Kids who used cell phones themselves had an 18% higher risk of behavior problems. And kids with both exposures had an 80% higher risk of behavior problems..."
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Tuesday, June 3, 2008
Good News In Our DNA: Defects You Can Fix With Vitamins And Minerals
2008.06.03
"In the PNAS paper, Rine, Marini and their colleagues report on their initial analysis of variants of a human enzyme called methylenetetrahydrofolate reductase, or MTHFR. The enzyme, which requires the B vitamin folate to work properly, plays a key role in synthesizing molecules that go into the nucleotide building blocks of DNA. Some cancer drugs, such as methotrexate, target MTHFR to shut down DNA synthesis and prevent tumor growth...Most scientists think that harmful mutations are disfavored by evolution, but Rine pointed out that this applies only to mutations that affect reproductive fitness. Mutations that affect our health in later years are not efficiently removed by evolution and may remain in our genome forever...The health effects of tuning up this enzyme in humans are unclear, he said, but folate is already known to protect against birth defects and seems to protect against heart disease and cancer. At least one defect in the MTHFR enzyme produces elevated levels in the blood of the metabolite homocysteine, which is linked to an increased risk of heart disease and stroke, conditions that typically affect people in their post-reproductive years..."In those people, supplementation of folate in the diet can reduce levels of that metabolite and reduce disease risk," Marini said...Marini and Rine credit Bruce Ames, a UC Berkeley professor emeritus of molecular and cell biology now on the research staff at Children's Hospital Oakland Research Institute, with the research that motivated them to look at enzyme variation. Ames found in the 1970s that many bacteria that could not produce a specific amino acid could do so if given more vitamin B6, and in recent years he has continued exploring the link between micronutrients and health..."Looked at in one way, Bruce found that you can cure a genetic disease in bacteria by treating it with vitamins," Rine said. Because the human genome contains about 6 billion DNA base pairs, each one subject to mutation, there could be between 3 and 6 million DNA sequence differences between any two people. Given those numbers, he reasoned that, as in bacteria, "there should be people who are genetically different in terms of the amount of vitamin needed for optimal performance of their enzymes.""
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"Good" bacteria may ease hay fever symptoms
2008.06.02
"'These data show that probiotic supplements modulate immune
responses...and may have the potential to alleviate the
severity of symptoms,' Claudio Nicoletti and colleagues at the
Institute of Food Research in Norwich, Britain"
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Red wine compound, Resveratrol, seen protecting heart from aging
2008.06.03
"...These mice experienced changes in their gene activity related to aging in a way very similar to mice that were placed on a so-called calorie restriction diet that slows the aging process by greatly cutting dietary energy intake...Most striking was how the resveratrol, like calorie restriction, blocked the decline in heart function typically associated with aging, according to Tomas Prolla, a University of Wisconsin professor of genetics...in this study, mice were given relatively low doses compared to the earlier research, and still experienced important aging-related benefits...They looked at the heart, brain and muscles, and said that the effect of resveratrol was strongest in the heart but did prevent some aging-related changes in the other tissues...Prolla said, "I think there's a high likelihood that our findings are applicable to humans."..."
Full study here
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Thursday, May 29, 2008
Exercise Cuts Cancer Death In Men
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Children Eat More Fruits And Vegetables If They Are Homegrown
2007.04.19
"'It was a simple, clear finding,' said Debra Haire-Joshu, Ph.D., director of Saint Louis University's Obesity Prevention Center and a study author. 'Whether a food is homegrown makes a difference. Garden produce creates what we call a 'positive food environment."..."When children are involved with growing and cooking food, it improves their diet," Haire-Joshu said. "Students at schools with gardens learn about math and science and they also eat more fruits and vegetables. Kids eat healthier and they know more about eating healthy. It's a winning and low-cost strategy to improve the nutrition of our children at a time when the pediatric obesity is an epidemic problem."
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Fruits, Vegetables And Teas May Protect Smokers From Lung Cancer
2008.05.29
— Tobacco smokers who eat three servings of fruits and vegetables per day and drink green or black tea may be protecting themselves from lung cancer, according to a first-of-its-kind study by UCLA cancer researchers...flavonoids that appeared to be the most protective included catechin, found in strawberries and green and black teas, kaempferol, found in Brussels sprouts and apples, and quercetin, found in beans, onions and apples...flavonoids protect against lung cancer by blocking the formation of blood vessels that tumors develop so they can grow and spread, a process called angiogenesis. They also stop cancer cells from growing, allowing for naturally programmed cell death, or apoptosis, to occur...The antioxidant properties found in the flavonoids also may work to counteract the DNA damaging effects of tobacco smoking, Zhang said, explaining why they affected the development of lung cancer in smokers but not in non-smokers..."The naturally occurring chemicals may be working to reduce the damage caused by smoking," Zhang said."
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Mediterranean diet may stop diabetes
2008.05.29
"A Mediterranean diet rich in fruits and vegetables -- already known to protect against heart disease -- also appears to help ward off diabetes... people who stuck closely to the diet were 83 percent less likely to develop type 2 diabetes...the protection appeared to extend to older people, smokers and volunteers with a family history of diabetes -- a group all the more prone to the disease -- shows the diet works..."
From Wiki ""abundant plant foods, fresh fruit as the typical daily dessert, olive oil as the principal source of fat, dairy products (principally cheese and yogurt), and fish and poultry consumed in low to moderate amounts, zero to four eggs consumed weekly, red meat consumed in low amounts, and wine consumed in low to moderate amounts". Total fat in this diet is "<> 35%" of calories, with saturated fat at 8% or less of calories."
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Wednesday, May 28, 2008
Buckthorn Leaves May Help Protect Against Liver Damage
2008.05.28
"Sea buckthorn (Hippophae rhamnoides) berries are well known for their cholesterol busting properties, but scientists in India say that its leaves are also rich in anti-oxidants and may help ward off liver disease...Indigineous to the mountainous regions of China and Russia, sea buckthorn has been shown to be rich in vitamin C, vitamin E, flavonoids and essential fatty acids. The leaves are also used to make a tea...liver damage was severely restricted in the rats given leaf extract..."
Ghengis Khan Wonder Berry Could Conquer Heart Disease: "ScienceDaily (Oct. 4, 2006) — Berries taken since the time of Ghengis Khan could form the basis of the next big thing in heart health. Sea buckthorn is a known source of biologically active chemicals and is used in Tibet, Mongolia, China and Russia for health drinks and various cosmetics."
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Organic Free Grazing Cows Produce Better Milk
2008.05.28
"‘We have known for some time that what cows are fed has a big influence on milk quality,’ explained Gillian Butler, livestock project manager for the Nafferton Ecological Farming Group at Newcastle University, who led the study. ‘What is different about this research is it clearly shows that on organic farms, letting cows graze naturally, using forage-based diet, is the most important reason for the differences in the composition between organic and conventional milk...grazing cows on organic farms in the UK produce milk which contains significantly higher beneficial fatty acids, antioxidants and vitamins than their conventional ‘high input’ counterparts...During the summer months, one of the beneficial fats in particular – conjugated linoleic acid, or CLA9 – was found to be 60% higher...‘We’ve shown that significant seasonal differences exist, with nutritionally desirable fatty acids and antioxidants being highest during the summer, when the cows are eating fresh grass and clover...higher concentrations of omega 3 fatty acids in milk from organic production systems than conventional ones...CLA, omega-3 fatty acids, vitamin E and carotenoids have all been linked to a reduced risk of cardiovascular disease and cancer. CLA is hugely popular in the US, where it is marketed as a nutritional supplement. However, synthetic supplements often contain compounds with a different chemical composition (isomer balance) than those occurring naturally in milk, resulting in an equal dose of both ‘good’ (i.e. CLA9, omega-3 fatty acid, vitamin E and carotenoids) and ‘less desirable’ fatty acids (i.e. omega-6 fatty acids and CLA10)...‘Switching to organic milk provides an alternative, natural way to increase our intake of nutritionally desirable fatty acids, vitamins and antioxidants without increasing our intake of less desirable fatty acids and synthetic forms of vitamin E,’ said Mrs Butler. ‘In organic milk, the omega-3 levels increase but the omega-6 does not, which helps to improve the crucial ratio between the two.’"
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Possible treatment for inflammatory bowel disease with probiotic
2008.05.28
"...a complex sugar molecule made naturally by a species of intestinal bacteria called Bacteroides fragilis prevented the development of an animal version of inflammatory bowel disease in laboratory mice..."We are colonized in our intestine normally with many bacteria -- 100 trillion or so," Dennis Kasper, a professor of medicine, microbiology and molecular genetics at Harvard Medical School...When the scientists exposed the mice to the "good" bacterium, Bacteroides fragilis, they were protected from an inflammatory bowel condition due to the action of a sugar molecule, called polysaccharide A, made by the bacterium...Mice that were given oral doses of just the sugar molecule also were protected...The sugar molecule worked by stimulating the mouse immune system to make a substance called interleukin-10, which changes the body's response to the disease-causing bacteria, dampening inflammation..."
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Sleep linked to brain cell creation - neurogenesis
2007.02.10
" Losing sleep may cause the brain to stop producing new brain cells, a study conducted by New Jersey's Princeton University has found...By depriving rats of sleep for 72 hours, the researchers found that those animals consequently had increased amounts of the stress hormone corticosterone, and produced significantly fewer new brain cells in the hippocampus...When the rats' sleep patterns were returned to normal a week later, their levels of nerve-cell production remained hindered for two weeks."
Four Days Of REM Sleep Deprivation Affects Forebrain, Long-term Memory In Rats: "ScienceDaily (Feb. 6, 2008)"
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Tuesday, May 27, 2008
Cocoa for Diabetes?
2008.05.27
"Compounds in Cocoa Could Help Ward Off Heart Complications...Patients who drank the high-flavonol cocoa for one month had their blood vessel function improve from severely impaired to normal. Drinking the low-dose flavanol cocoa did not result in any significant changes in blood vessel function...dietary flavonols might have an important impact as part of a healthy diet in the prevention of cardiovascular complications in diabetic patients..."
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Studies link lead to adult crime, brain damage
2008.05.27
"Exposure to lead in early childhood or in the womb can cause permanent brain damage that may even cause criminal behavior, researchers reported on Tuesday...Two studies showed that people with high levels of lead in childhood grew up with blocks of missing brain cells -- and they also were far more likely to be arrested for crimes, especially violent crimes...The effect is so strong that it may account for a large percentage of crimes in inner-city areas, where old houses are far more likely to have lead paint, said Kim Dietrich of the University of Cincinnati in Ohio, who led one of the studies in the Public Library of Science journal PLoS Medicine...Those with high lead levels before birth and during early childhood had higher rates of arrest than those with lower lead levels. About 55 percent of the now-grown children had at least one arrest, 28 percent involving drugs and 27 percent serious motor vehicle violations."..Lower income, inner-city children remain particularly vulnerable to lead exposure," Dietrich said...more than 1 percent of total gray matter in the brain was missing. "The most affected regions included frontal gray matter, specifically the anterior cingulate cortex," Cecil's team wrote in a second study. This region is responsible for mood regulation and decision-making.
Men were far more affected than women.
"Our findings also suggest that this structural change is permanent," they wrote.
The implications are profound, Dietrich said. "Usually the effects of lead poisoning are irreversible," he said..."
This is an unbelievably important story. If the research is correct, lead is clearly much worse than previously imagined in derailing proper brain development and function in a significant portion of our population. The next administration needs to make this a priority. And the press needs to make this story number #1 tomorrow and for the next few days. Will they?More on lead -
Childhood Lead Exposure Is Associated With Decreased Brain Volume In Adults: ScienceDaily 2008.05.27 "...There was a "dose-response" effect--in other words, the greatest brain volume loss was seen in participants with the greatest lead exposure in childhood. The specific regions of the brain involved were those responsible for organizing actions, decisions, and behaviors (known as "executive functions"), regulating behaviors, and coordinating fine movements (known as "fine motor control")..."
Prenatal Exposure To Lead Linked To Obesity In Males: "ScienceDaily (Feb. 22, 2008)
Early Lead Exposure Impedes Recovery From Brain Injury: "ScienceDaily (Dec. 4, 2007)
Stimulating Environment Protects Brain Against Damage From Lead Exposure: "ScienceDaily (Apr. 3, 2001)
Children More Vulnerable To Harmful Effects Of Lead: "ScienceDaily (May 5, 2008)
Very Low Lead Levels Linked With IQ Deficits, According To NEJM Study: "ScienceDaily (Apr. 17, 2003)
Study Links Lead Exposure To Antisocial Behavior: "ScienceDaily (Mar. 1, 2002)"
Pitt Research Shows Early Lead Exposure Is A Significant Cause Of Juvenile Delinquency: "ScienceDaily (May 16, 2000)"
Lead In The Environment Causes Violent Crime, Reports University Of Pittsburgh Researcher: "ScienceDaily (Feb. 26, 2005)
Even Low Lead Exposure Linked To ADHD: "ScienceDaily (Dec. 6, 2007)"
Does vitamin C intake protect against lead toxicit...[Nutr Rev. 2000] - PubMed Result: "Department of Foods and Nutrition, Faculty of Gerontology, University of Georgia, Athens 30602, USA."
Chelation Therapy for Childhood Lead Poisoning:: http://www.hsph.harvard.edu/organizations/DDIL/chelation.htm
Lead Poisoning-Topic Overview: WebMD
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Vitamin D doesn't cut prostate cancer risk
2008.05.27
"..."In our study, we didn't see any protective effect of vitamin D in relation to prostate cancer risk," Jiyoung Ahn of the U.S. National Cancer Institute...Some studies have indicated it might provide other benefits. For example, one study published in January found that people with low vitamin D levels had an elevated risk for heart attack, heart failure and stroke, suggesting it may protect against cardiovascular disease..."
But remember...
HEALTH & LONGEVITY: Vitamin D may slow aging
HEALTH & LONGEVITY: Vitamin D update (roundup of recent Vitamin D research)
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Monday, May 26, 2008
Experts Revisit Food Additives and ADHD
2008.05.22
"Kemp cited a recent controlled trial showing an increase in hyperactivity among children without ADHD who were fed a diet high in food colorings and the preservative sodium benzoate...of 22 studies conducted between 1975 and 1994, 16 found dietary modification to have a positive impact on at least some children with ADHD..."
Rember that sodium benzoate is thought to inactivate certain vital parts of DNA.
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Gum Disease May Raise Cancer Risk
2008.05.27
"...Compared to men with healthy gums, men with a history of gum disease were:
- 14% more likely to develop cancer overall
- 49% more likely to develop kidney cancer
- 54% more likely to develop pancreatic cancer
- 30% more likely to develop blood cancers
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