Policosanol is ineffective in the treatment of hypercholesterolemia: a randomized controlled American Journal of Clinical Nutrition, Vol. 84, No. 6, 1543-1548, December 2006 "No significant differences in the change in LDL cholesterol were observed between the placebo (n = 20) and policosanol (n = 20) groups. Also, no significant changes in secondary outcome measures, including total cholesterol, HDL cholesterol, triacylglycerol, C-reactive protein, and nuclear magnetic resonance spectroscopy–determined profiles were observed. Policosanol was well tolerated, and no significant adverse events were noted"
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