Wednesday, August 15, 2007

Polyphenols blunt menopausal effects in rats

Plant compounds blunt menopausal effects in rats Reuters/Yahoo!News "Women who enter menopause often develop high blood pressure, insulin resistance (a risk factor for type 2 diabetes), and memory loss. New research conducted in menopausal rats suggests that polyphenols - compounds found in grapes, soy, and kudzu -- may blunt some of these side effects associated with menopause...Wyss reported that, in estrogen-depleted rats, kudzu root extract reduced blood pressure, elevated by a high-salt diet, by more than 50 percent. Kudzu also lowered blood sugar, insulin levels and the fat hormone leptin..."Kudzu has estrogen-like elements,"...Wyss and colleagues also observed that estrogen-depleted rats fed polyphenols from grape seed seemed to be protected against high blood pressure as well as a decline in short-term and long-term....Other studies from the Wyss lab indicate that polyphenols in soy foods also protect against high blood pressure in menopausal rats...For menopausal symptoms, grapes, soy and kudzu "may be useful" treatments or add-on treatments to other therapies, Wyss concluded. He said his team is also looking at the effects of adding these polyphenols to conventional treatments for diabetes and lipid control."

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