Wednesday, October 17, 2007

Choline, An Alternative Therapy For Asthma

Choline, An Alternative Therapy For Asthma - Medical News Today
2007.09.28
"...Choline treatment inhibits the development of airway hyperresponsiveness (AHR) and eosinophilic inflammation in the lungs. This reduction of AHR is accompanied by a reduction in immunoglobulin E antibody (IgE) and other inflammatory parameters like type 2 T-helper cell (Th2) cytokines, in a manner comparable with current therapy of asthma. Choline treatment also downregulates mucus production and prevents airway obstruction...Choline supplementation increases membrane phosphatidyl choline and thereby decreases the mediator release from human basophils... The results of the present study are encouraging, as choline therapy may enable to substitute or reduce the dosage and side effects of steroid therapy in asthma."

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