Gum disease linked with pancreatic cancer in study Reuters/Yahoo!News 1/16/07 "men who had periodontal disease had a 63 percent higher risk of developing pancreatic cancer than men with healthy teeth and gums. Men who lost teeth within the past four years were especially likely to develop pancreatic cancer..."Most convincing was our finding that never-smokers (with gum disease) had a two-fold increase in risk of pancreatic cancer," said Dominique Michaud of the Harvard School of Public Health, who led the study...Michaud's team studied 48,000 men taking part in the Health Professionals Follow-Up Study between 1986 and 2002...Pancreatic cancer is the fourth-leading cause of cancer deaths in the United States. It will kill 95 percent of the 32,000 people who get it this year...Periodontal disease is caused when bacteria infect the gums and the infection gradually destroys bone..."The association may be due to systemic (throughout the body) inflammation and/or increased levels of carcinogenic compounds generated by bacteria in the oral cavity of individuals with periodontal disease,"...The men with gum disease seemed to have chronic inflammation -- their levels of a protein called C-reactive protein, a measure of inflammation, were 30 percent higher than those of men with healthy gums...Or the bacteria responsible for the gum loss could produce nitrosamines, which are compounds known to cause cancer "
More on nitrosamines here.
More on C-reactive protein and ideas on how to lower it here.
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